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What is Candida auris (C.auris)?

Dec. 21, 2025

Scientists recently discovered a genetic process which could unlock new ways to treat mysterious and deadly Candida auris.

About Candida auris (C.auris):

  • It is a fungal pathogen that is often multi-drug-resistant.
  • This pathogen can live on the skin, inside the human body (e.g. in the gut), or in the environment.
  • It is capable of causing invasive infections in the human body.
  • auris causes serious infections such as bloodstream infections, meningitis, bone infections, burns/wound infections, and urinary tract infections.
  • It was first identified in Japan.
  • How is it contracted?
    • Most cases of the fungus have been reported in healthcare settings, such as hospitals and nursing homes.
    • It is generally thought to be spread through contact with contaminated surfaces or by person-to-person transmission.
    • People who are already suffering from other medical conditions, recent hospital stays, and invasive devices are most at risk of contracting the fungus.
  • How does the fungus act on the body? There are two ways auris can affect the body,
    • The fungus can either live on a specific region, such as the skin, rectum, or mouth, in a process called “asymptomatic colonization,” where a patient has no symptoms but can spread it to other people.
    • It can enter the bloodstream or wounds, where it can cause severe invasive infections.
  • Symptoms:
    • Its symptoms are often similar to those of other common diseases, and hence diagnosis is difficult.
    • The most common symptoms of C. auris include fever and chills that don’t go away after treatment with antibiotics.
  • Mortality Rate: It is estimated to be between 30-60%.
  • Treatment:
    • Most C. auris infections are treatable with antifungal drugs called echinocandins.
    • However, some C. auris infections are resistant to the main types of antifungal medications, making them more difficult to treat.
    • In this situation, multiple antifungals at high doses may be required to treat the infection.

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