What are Peptides?

May 4, 2024

Scientists have developed a promising therapy using cow-derived peptides to combat deadly drug-resistant bacteria, offering a new approach to tackle severe infections resistant to conventional antibiotics.

About Peptides:

  • They are chains of amino acids that are naturally found in the body. The amino acids in a peptide are connected to one another in a sequence by bonds called peptide bonds.
  • Peptides vs. Proteins:
    • Proteins and peptides are fundamental components of cells that carry out important biological functions
    • Typically, peptides are distinguished from proteins by their shorter length, although the cut-off number of amino acids for defining a peptide and protein can be arbitrary.
    • Traditionally, peptides are defined as molecules that consist of between 2 and 50 amino acids.
    • Meanwhile, proteins are long molecules made up of multiple peptide subunits, and are also known as polypeptides.
    • In addition, peptides tend to be less well defined in structure than proteins, which can adopt complex conformations known as secondary, tertiary and quaternary structures. 
    • Proteins can be digested by enzymes (other proteins) into short peptide fragments.
  • Functions of Peptides:
    • The body makes lots of different peptides, each of which has a different role.
    • They may provide pro-aging support, anti-inflammatory, or muscle-building properties.
    • Some peptides act as hormones, which are molecules, that when released from cells, affect other areas of the body.
    • Due to the potential health benefits of peptides, many supplements are available that contain peptides that manufacturers have derived either from food or made synthetically.

What are Amino Acids?

  • They are molecules that combine to form proteins. Amino acids and proteins are the building blocks of life. There are 20 different amino acids.
  • A protein consists of one or more chains of amino acids(called polypeptides) whose sequence is encoded in a gene.
  • Some amino acids can be synthesized in the body, but others (essential amino acids) cannot and must be obtained from a person’s diet.
  • The nine essential amino acids are: histidine, isoleucine, leucine, lysine, methionine, phenylalanine, threonine, tryptophan and valine.