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Rabies

Dec. 27, 2025

According to a paper published in One Health, of the 59,000 rabies-mediated human deaths in the world every year, India represents a third, around 20,000, and more than any other country.

About Rabies:

  • Rabies is a vaccine-preventable, zoonotic, viral disease.
  • It is caused by the Rabies virus (RABV) which affects the central nervous system.
  • It infects mammals, including dogs, cats, livestock and wildlife.
  • It is one of the Neglected Tropical Diseases (NTD)that predominantly affects already marginalized, poor and vulnerable populations.
  • Transmission: It spreads to people and animals via saliva, usually through bites, scratches, or direct contact with mucosa (e.g. eyes, mouth, or open wounds).
  • Clinically, it has two forms: 
    • Furious rabies: It is characterized by hyperactivity and hallucinations.
    • Paralytic rabies: It is characterized by paralysis and coma.
  • Symptoms of Rabies:
    • The incubation period for rabies is typically 2–3 monthsbut may vary from one week to one year.
    • Initial symptoms include generic signs like fever, pain, and unusual or unexplained tingling, pricking, or burning sensations at the wound site. 
    • As the virus moves to the central nervous system, progressive and fatal inflammation of the brain and spinal cord develops. 
    • Once the virus infects the central nervous system and clinical symptoms appear, rabies is fatal in 100% of cases.
  • Prevention: Vaccinating dogs, including puppies, is the most cost-effective strategy for preventing rabies in people because it stops the transmission at its source.

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