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Infectious Bovine Rhinotracheitis

Sept. 30, 2025

Recently, Indian Immunologicals (IIL) has launched India’s first indigenously developed glycoprotein E (gE) deleted DIVA marker vaccine against infectious bovine rhinotracheitis (IBR).

About Infectious Bovine Rhinotracheitis:

  • It is endemic in India and caused by Bovine Herpes Virus (BHV-1).
    • BoHV-1 is a member of the genus Varicellovirus in the subfamily Alphaherpesvirinae.
  • It is a disease of domestic and wild cattle.
  • There are three forms: respiratory, genital and encephalitic, the first two are more common.
  • Transmission: The disease is transmitted through the aerosol route and affects reproductive systems. It is also transmitted by semen from bulls to milch animals.
  • Symptoms of Infectious Bovine Rhinotracheitis
    • It is characterised by clinical signs of the upper respiratory tract, such as a (muco)purulent nasal discharge, hyperaemia of the muzzle (red nose disease) and by conjunctivitis.
    • Signs of general illness are fever, depression, inappetence, abortions and reduced milk yield.
  • Impacts on Bovines: Infertility, abortions and lower milk productivity are some of the major impacts of the disease.
  • Treatment: There is no vaccine available in India and there is no specific treatment against this disease thus far.

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