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Alanine aminotransferase

July 31, 2026

Recently, the Union Health Ministry has urged people to monitor alanine aminotransferase (ALT) levels as an early indicator of liver injury.

About Alanine aminotransferase:

  • Also known as serum glutamic-pyruvic transaminase (SGPT), it is an enzyme found predominantly inside liver cells.
  • It is also found in other tissues such as the kidneys, heart, and muscle cells.
  • It plays a crucial role in metabolism, turning food into energy.
  • ALT is one component of the liver function test, which includes other liver enzymes and measures of liver function.
  • The ALT test is often part of an initial screening for liver disease.
  • What is an ALT test?
    • An ALT test is also known as a serum glutamic-pyruvic transaminase (SGPT) test or an alanine transaminase test.
    • When liver cells are damaged or inflamed, ALT leaks into the bloodstream. This causes serum ALT levels to rise.
    • An increase in ALT is often the first sign of a liver problem, and ALT is often elevated before other symptoms appear.
    • ALT testing is performed on a blood sample.

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